We have updated the database with 6,132 new haplotypes from 128 different origins.
We came across a novel block deletion of 9 nucleotides preceding the AC-repeat region in HVS-III. This changes the earlier SAM2 alignment in that region (see figure below) and leads to a phylogenetically more plausible alignment.
We have updated the database with 8,227 new haplotypes from 26 different countries (including 5 updates from CR to full mitogenome).
EMPOP now uses the new developed query engine SAM2 Huber et al 2018 that is based on SAM Röck et al 2011
The tolerance level of EMMA was downsized from 0.3 to 0.1 to allow for a finer haplogroup estimation of mtDNA haplotypes. Extensive testing on a data set comprising 86,048 haplotypes suggested that this reduction would be beneficial for forensically relevant haplogrouing. Especially haplotypes previously assigned to haplogroups H, L3 and M benefit from a more accurate classification.