Contribute

The board of the International Society of Forensic Genetics (ISFG) and the editors of Forensic Science International: Genetics and International Journal of Legal Medicine invited EMPOP to logistically organize and perform quality control (QC) of mtDNA sequences in the course of manuscript preparations for the journals. Before mtDNA population papers are put forward to the editors for review, the authors are requested to submit the data to EMPOP. After positive evaluation, the authors will be contacted by EMPOP with the respective EMPOP accession numbers that serve as indicator of successful QC for the editors and reviewers. The necessary steps for submission of mtDNA sequences to EMPOP are outlined below.

Step 1

Prepare your sequence data as shown in the tutorial. An example can be downloaded from the EMPOP webpage here that can also be used as template. The emp-file is a tab delimited text file that can be created using standard text software or MS Excel (then, save file under .txt format and rename "txt" by "emp"). The first 2 lines specify individual details of the dataset and origin of the samples. Further lines list the mtDNA haplotypes headed by their sequence range(s). Note that a given sequence range is applied to all mtDNA haplotypes following this range until a new range is defined (range lines are defined by "#!"). Text lines, e.g. for individual comments, need to be identified using the "#" symbol.

Step 2

Submit your file to EMPOP by Email to EMPOP. The data will be quality checked for format, clerical error, sequence range violation, reference error, designation of indels, phantom mutation using in-house software and Network.

Step 3

After EMPOP evaluation communication may follow with respect to individual sequences. Once your data passed QC you will receive the emp-file of your data together with the EMPOP accession number(s) for your data. Please provide accession number(s) together with your manuscript to the editor of the journal.

Step 4

Data that successfully passed QC will be uploaded onto EMPOP.